Review paper
Reactive oxygen species produced by altered tumor metabolism impacts cancer stem cell maintenance
Abstract
Controlling reactive oxygen species (ROS) at sustainable levels can drive multiple facets of tumor biology, including within the cancer stem cell (CSC) population. Tight regulation of ROS is one key component in CSCs that drives disease recurrence, cell signaling, and therapeutic resistance. While ROS are well-appreciated to need oxygen and are a product of oxidative phosphorylation, there are also important roles for ROS under hypoxia. As...
Paper Details
Title
Reactive oxygen species produced by altered tumor metabolism impacts cancer stem cell maintenance
Published Date
Aug 1, 2021
Journal
Volume
44
Pages
101953 - 101953
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