Original paper
PAX8 lineage-driven T cell engaging antibody for the treatment of high-grade serous ovarian cancer
Abstract
High-grade serous ovarian cancers (HGSOC) represent the most common subtype of ovarian malignancies. Due to the frequency of late-stage diagnosis and high rates of recurrence following standard of care treatments, novel therapies are needed to promote durable responses. We investigated the anti-tumor activity of CD3 T cell engaging bispecific antibodies (TCBs) directed against the PAX8 lineage-driven HGSOC tumor antigen LYPD1 and demonstrated...
Paper Details
Title
PAX8 lineage-driven T cell engaging antibody for the treatment of high-grade serous ovarian cancer
Published Date
Jul 21, 2021
Journal
Volume
11
Issue
1
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Notes
History