Cardiac measurement of hyperpolarized ¹³C metabolites using metabolite‐selective multi‐echo spiral imaging

Purpose Noninvasive imaging with hyperpolarized (HP) pyruvate can capture in vivo cardiac metabolism. For proper quantification of the metabolites and optimization of imaging parameters, understanding MR characteristics such as s of the HP signals is critical. This study is to measure in vivo cardiac s of HP [1‐ 13 C]pyruvate and the products in rodents and humans. Methods A dynamic 13 C multi‐echo spiral imaging sequence that acquires [ 13...