Original paper
Identification of Thymidine Phosphorylase as a Potential Therapeutic Target for Bone Loss Associated Periprosthetic Osteolysis
Abstract
Background: Macrophage-derived factors are generally thought to play a key role in the pathogenesis of aseptic loosening though initiating periprosthetic inflammation and pathological bone resorption. Therefore, the aim of this study was to identify macrophage-derived factors that promote osteoclast differentiation and periprosthetic bone destruction.
Methods: We examined the effects of 12 macrophage-derived factors that were identified by...
Paper Details
Title
Identification of Thymidine Phosphorylase as a Potential Therapeutic Target for Bone Loss Associated Periprosthetic Osteolysis
Published Date
Jan 1, 2021
Journal
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Notes
History