Dual cross-linked organic-inorganic hybrid hydrogels accelerate diabetic skin wound healing

Limited therapeutic options are available for healing chronic non-self-healing diabetic wounds, which are characterized by bacterial infection as well as a hypoxic microenvironment. Here, we report a simple and efficient strategy to generate a multifunctional organic–inorganic hybrid hydrogel to simultaneously overcome these problems. This hybrid hydrogel is composed of a dual cross-linked silk fibroin (SF) network with hemoglobin (Hb) and...