Review paper

IL-6 inhibition in the treatment of COVID-19: A meta-analysis and meta-regression

Volume: 82, Issue: 5, Pages: 178 - 185
Published: May 1, 2021
Abstract
ObjectivesMultiple RCTs of interleukin-6 (IL-6) inhibitors in COVID-19 have been published, with conflicting conclusions. We performed a meta-analysis to assess the impact of IL-6 inhibition on mortality from COVID-19, utilising meta-regression to explore differences in study results.MethodsSystematic database searches were performed to identify RCTs comparing IL-6 inhibitors (tocilizumab and sarilumab) to placebo or standard of care in adults...
Paper Details
Title
IL-6 inhibition in the treatment of COVID-19: A meta-analysis and meta-regression
Published Date
May 1, 2021
Volume
82
Issue
5
Pages
178 - 185
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