Dynamics of hunchback translation in real-time and at single-mRNA resolution in the Drosophila embryo

Volume: 148, Issue: 18
Published: Apr 15, 2021
Abstract
The Hunchback (Hb) transcription factor is crucial for anterior-posterior patterning of the Drosophila embryo. The maternal hb mRNA acts as a paradigm for translational regulation due to its repression in the posterior of the embryo. However, little is known about the translatability of zygotically transcribed hb mRNAs. Here, we adapt the SunTag system, developed for imaging translation at single-mRNA resolution in tissue culture cells, to the...
Paper Details
Title
Dynamics of hunchback translation in real-time and at single-mRNA resolution in the Drosophila embryo
Published Date
Apr 15, 2021
Volume
148
Issue
18
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