Epistemology

Philosophy

Pathology

Microbiome

Gut–brain axis

Immunology

Dysbiosis

Flora (microbiology)

Disease

Human health

Human disease

Gut microbiome

Bacteria

Gut flora

Genetics

Bioinformatics

Medicine

Biology

Mechanism (biology)

Human microbiome

Environmental health

Frontiers in Cellular and Infection Microbiology

The human gut microbiome is a huge microbial community that plays an irreplaceable role in human life. With the further development of research, the influence of intestinal flora on human diseases has been gradually excavated. Gut microbiota (GM) dysbiosis has adverse health effects on the human body that will lead to a variety of chronic diseases. The underlying mechanisms of GM on human diseases are incredibly complicated. This review focuses on the regulation and mechanism of GM on neurodegenerative diseases, cardiovascular diseases, metabolic diseases and gastrointestinal diseases, thus providing a potential target for the prevention and treatment of disease.

Role and Mechanism of Gut Microbiota in Human Disease