Original paper
Phase separation in genome organization across evolution
Abstract
Phase separation is emerging as a paradigm to explain the self-assembly and organization of membraneless bodies in the cell. Recent advances show that this principle also extends to nucleoprotein complexes, including DNA-based structures. We discuss here recent observations on the role of phase separation in genome organization across the evolutionary spectrum from bacteria to mammals. These findings suggest that molecular interactions amongst...
Paper Details
Title
Phase separation in genome organization across evolution
Published Date
Aug 1, 2021
Journal
Volume
31
Issue
8
Pages
671 - 685
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Notes
History