Identification of differentially expressed genes in synovial tissue of osteoarthritis based on a more robust integrative analysis method

This study aimed to identify osteoarthritis (OA) related genes based on microarray data in synovium with a more robust integrative analysis method. Four series GSE55457, GSE12021, GSE55235, and GSE55584 (36 OA and 29 normal samples) were downloaded from the Gene Expression Omnibus database. Differentially expressed genes (DEGs) of GSE55457, GSE12021, and GSE55235 were identified using the LIMMA package. Overlapping DEGs from the intersection of...