Quantifying misfolded protein oligomers as drug targets and biomarkers in Alzheimer and Parkinson diseases

Volume: 5, Issue: 4, Pages: 277 - 294
Published: Feb 15, 2021
Abstract
Protein misfolding and aggregation are characteristic of a wide range of neurodegenerative disorders, including Alzheimer and Parkinson diseases. A hallmark of these diseases is the aggregation of otherwise soluble and functional proteins into amyloid aggregates. Although for many decades such amyloid deposits have been thought to be responsible for disease progression, it is now increasingly recognized that the misfolded protein oligomers...
Paper Details
Title
Quantifying misfolded protein oligomers as drug targets and biomarkers in Alzheimer and Parkinson diseases
Published Date
Feb 15, 2021
Volume
5
Issue
4
Pages
277 - 294
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