Micronutrient

Psychological intervention

Food fortification

Vitamin

Biology

Retinol

Endocrinology

Psychiatry

Fortification

Anemia

Food science

Malnutrition

Environmental health

Pediatrics

Fortified Food

Population

Internal medicine

Vitamin A deficiency

Medicine

Anthropometry

Pathology

International Journal of Environmental Research and Public Health

Food fortification programs have been conducted in several countries to overcome micronutrient deficiency and related problems with various degrees of effectiveness. Available information regarding the success of food fortification programs in some developing countries, including Indonesia, is still limited. Thus, this study conducts a systematic review of the effects of food fortification of mothers and children using biochemical and anthropometric measures focusing on linear growth. Three databases were used in the literature search, namely PubMed, Science Direct and Google Scholar. Fifteen articles were included for analysis from 517 studies found consisting of Indonesian and English articles published from 2000 to June 2020. Fortification of iron, vitamin A, and iodine can increase the level of hemoglobin, serum ferritin, and serum retinol and median urine iodine excretion, especially in toddlers and schoolchildren. However, multinutrient fortification interventions were associated with various effects on hemoglobin, serum ferritin, and serum retinol but a positive association was found with linear growth indicators in the form of body length for age. The effectiveness of food fortification in reducing the prevalence of stunting still needs more and stronger evidence through studies with large sample size and longer duration.

Effectiveness of Food Fortification in Improving Nutritional Status of Mothers and Children in Indonesia