Evaluación del uso de antibióticos en pacientes ingresados a una unidad de cuidados intensivos con asistencia de terapias de reemplazo renal continua en un hospital de alta complejidad de la ciudad de Bogotá

Published on Sep 14, 2020
Abstract
References62
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#2Anita Będźkowska (Gdańsk Medical University)H-Index: 1
Last. Paweł Wiczling (Gdańsk Medical University)H-Index: 20
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BACKGROUND: The primary objective of this study was to develop a population pharmacokinetic model of meropenem, based on the population of critically ill adult patients undergoing CRRT. The secondary one was to examine the relationship between patient characteristics (covariates) and individual PK parameters. Finally, we aimed to perform Monte Carlo simulations to assess the probability of target attainment (PTA) of %T > MIC considering the uncertainty of PK parameters. MATERIALS AND METHODS: Th...
2 CitationsSource
#1Brian M. Hoff (NU: Northwestern University)H-Index: 4
#2Jenana H. Maker (UC Davis: University of California, Davis)H-Index: 1
Last. Brett H. Heintz (UI: University of Iowa)H-Index: 6
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Objective: To summarize current antibiotic dosing recommendations in critically ill patients receiving intermittent hemodialysis (IHD), prolonged intermittent renal replacement therapy (PIRRT), and...
25 CitationsSource
#1Jorge Gonzáles Mendoza (UPCH: Cayetano Heredia University)H-Index: 1
#2Ciro Maguiña Vargas (UPCH: Cayetano Heredia University)H-Index: 9
Last. Flor de María González Ponce (UPCH: Cayetano Heredia University)H-Index: 1
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El uso de los antibioticos desde los anos 40 del siglo pasado permitio disminuir en forma importante y notable la morbilidad y mortalidad a nivel mundial. Sin embargo, la aparicion de la resistencia antimicrobiana ha hecho que el tratamiento de las enfermedades infecciosas, se vuelva una tarea desafiante para el medico que debe brindar opciones terapeuticas, racionales y basadas en evidencias para mejorar la salud de los pacientes. Esta revision brinda una vision panoramica sobre la gravedad de ...
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Resumen La magnitud del impacto de la resistencia a antibioticos (RA) es ahora bien reconocida. La implementacion de medidas para su control es imprescindible, pero, para que esta sea eficaz y rentable, debe ser guiada por el conocimiento previo del problema, un conocimiento lo mas actualizado, real y completo posible. Sin embargo, la dimension actual de la RA es dificil de cuantificar debido a la alta heterogeneidad en la recopilacion de datos, la existencia de grandes lagunas en la capacidad d...
2 CitationsSource
#1Jorge Enrique Echeverri (UMNG: Military University Nueva Granada)H-Index: 2
#2Alejandra Molano (Del Rosario University)H-Index: 1
espanolDel 6 al 23% de los pacientes con lesion renal aguda (LRA) en unidades de cuidados intensivos (UCI) requieren apoyo renal, siendo la terapia continua una modalidad de alta frecuencia de uso en el paciente criticamente enfermo. Si bien el objetivo general de las terapias de reemplazo renal continuo (TRRC) es restablecer el equilibrio hidrico y acido-base, junto con la eliminacion de toxinas uremicas e inflamatorias relacionadas con la perdida de depuracion renal y la disfuncion multiorgani...
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#1Alicia I Fayad (Boston Children's Hospital)H-Index: 3
#2Daniel G Buamscha (Boston Children's Hospital)H-Index: 2
Last. Agustín Ciapponi (Cochrane Collaboration)H-Index: 34
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BACKGROUND: Acute kidney injury (AKI) is a common condition among patients in intensive care units (ICUs), and is associated with high death. Renal replacement therapy (RRT) is a blood purification technique used to treat the most severe forms of AKI. The optimal time to initiate RRT so as to improve clinical outcomes remains uncertain.This review complements another Cochrane review by the same authors: Intensity of continuous renal replacement therapy for acute kidney injury. OBJECTIVES: To ass...
18 CitationsSource
#1Marcela Hernández (Universidad de La Sabana)H-Index: 1
#2Gabriel Fernando Tribiño (Universidad de La Sabana)H-Index: 1
Last. Carlos A. Bustamante (Universidad de La Sabana)H-Index: 3
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Introduction: Drug-drug interactions occur more frequently in intensive care units than in other services. However, in Colombia, there are few studies on this problem in critically ill patients. Objectives: To characterize potential drug-drug interactions generated from prescriptions during hospitalization in an intensive care unit and to determine factors associated with their onset. Materials and methods: A retrospective cohort was assembled with patients hospitalized in an intensive care unit...
6 CitationsSource
#1Jesus Ruiz (IPN: Instituto Politécnico Nacional)H-Index: 6
#2Cassandra Favieres (IPN: Instituto Politécnico Nacional)H-Index: 1
Last. Paula Ramirez (IPN: Instituto Politécnico Nacional)H-Index: 25
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Background Continuous renal replacement therapy (CRRT) is common practice in critical care patients with acute renal failure. Objectives To evaluate the adequacy of antimicrobial doses calculated based on the total drug clearance and dose recommended by different guides in critically ill patients undergoing CRRT. Methods Retrospective observational study. Patients admitted to a critical care unit during May 2014 to May 2016 and subjected to CRRT were included. The recommended dose was establishe...
4 CitationsSource
#1Zhiyong Peng (WHU: Wuhan University)H-Index: 21
#2Kaijiang Yu (Society of Critical Care Medicine)H-Index: 1
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Abstract Purpose Acute kidney injury (AKI) has become a major medical and financial burden in China along with the rest of the world. There have been considerable advances in the understanding of the epidemiology and pathogenesis of AKI. However, there is no consensus regarding the optimal care for patients. The Acute Disease Quality Initiative (ADQI) 19 meeting focused on identifying and designing relevant and achievable AKI-related studies in China. Materials & methods The working group develo...
3 CitationsSource
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