Nanogold-loaded chitosan nanocomposites for pH/light-responsive drug release and synergistic chemo-photothermal cancer therapy

Stable and biocompatible nano-agents that stimulate the combined cancer therapy are of great necessity. Herein, a ternary system composed of optimally prepared chitosan nanoparticles (ChNPs) efficiently encapsulating 5-Fluorouracil (5-FU) and loaded by gold nanoparticles (AuNPs) was employed for synergistic chemo-photothermal therapy. The composed [email protected] nanocomposites (NCs) combine the features of ChNPs, 5-FU, and AuNPs and exhibit...