An Overview of the Safety Profile, Advantages and Disadvantages of mRNA Based Vaccines in the SARS-CoV-2 Pandemic

Messenger ribonucleic acid (mRNA) gene expression and vaccine technology has certain advantages and disadvantages compared to traditional vaccine methods (live attenuated, inactive, protein subunit) and new generation systems (DNA-deoxyribonucleic acid-and viral vectors).mRNA vaccines have a design advantage since the expression system needs to cross a single barrier (cell membrane) and reach the ribosomes, also there is no risk of insertional...