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Review paper

Model‐Informed Drug Development for Anti‐Infectives: State of the Art and Future

Volume: 109, Issue: 4, Pages: 867 - 891
Published: Feb 9, 2021
Abstract
Model‐informed drug development (MIDD) has a long and rich history in infectious diseases. This review describes foundational principles of translational anti‐infective pharmacology, including choice of appropriate measures of exposure and pharmacodynamic (PD) measures, patient subpopulations, and drug‐drug interactions. Examples are presented for state‐of‐the‐art, empiric, mechanistic, interdisciplinary, and real‐world evidence MIDD...
Paper Details
Title
Model‐Informed Drug Development for Anti‐Infectives: State of the Art and Future
Published Date
Feb 9, 2021
Volume
109
Issue
4
Pages
867 - 891
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