Sex hormones and acne: State of the art

Summary Acne is an androgen‐dependent inflammatory disease of sebaceous follicles. Herein, we reviewed and discussed the underlying pathways of androgen biosynthesis and metabolism, non‐genomic regulation of androgen receptor expression and function, posttranslational regulation of androgen excess in acne and acne‐associated syndromes, such as polycystic ovary syndrome, and congenital adrenal hyperplasia. We provide insights into the involvement...