Original paper
A multilayered post-GWAS assessment on genetic susceptibility to pancreatic cancer
Abstract
Pancreatic cancer (PC) is a complex disease in which both non-genetic and genetic factors interplay. To date, 40 GWAS hits have been associated with PC risk in individuals of European descent, explaining 4.1% of the phenotypic variance.We complemented a new conventional PC GWAS (1D) with genome spatial autocorrelation analysis (2D) permitting to prioritize low frequency variants not detected by GWAS. These were further expanded via Hi-C map (3D)...
Paper Details
Title
A multilayered post-GWAS assessment on genetic susceptibility to pancreatic cancer
Published Date
Feb 1, 2021
Journal
Volume
13
Issue
1
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Notes
History