Dynamic exercise changes in venous pressure and liver stiffness in Fontan patients: effects of Treprostinil

Background: Systemic venous hypertension and low cardiac output are believed to be important mediators of liver injury after the Fontan procedure. Pulmonary vasodilators have the potential to improve such haemodynamics. The aim of this study was to assess the acute effects of exercise on liver stiffness and venous pressures and to assess the impact of inhaled Treprostinil on this response. Methods: In this prospective, double-blind,...