Highly redundant neuropeptide volume co-transmission underlying episodic activation of the GnRH neuron dendron
Abstract
The necessity and functional significance of neurotransmitter co-transmission remains unclear. The glutamatergic 'KNDy' neurons co-express kisspeptin, neurokinin B (NKB), and dynorphin and exhibit a highly stereotyped synchronized behavior that reads out to the gonadotropin-releasing hormone (GnRH) neuron dendrons to drive episodic hormone secretion. Using expansion microscopy, we show that KNDy neurons make abundant close, non-synaptic...
Paper Details
Title
Highly redundant neuropeptide volume co-transmission underlying episodic activation of the GnRH neuron dendron
Published Date
Jan 19, 2021
Journal
Volume
10
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