“One stroke drawing” of poly(ribonucleic acids) with different aptamer functions for sensing probes

Using polymerase chain reaction (PCR)-mediated recombination, single ribonucleic acid (RNA) chains containing bifunctional RNA sequences involving substrate binding and phosphorescent signaling were prepared. For substrate binding and phosphorescent labeling, thrombin- or lysozyme-binding and ruthenium complex-binding RNA aptamer sequences were used. It was demonstrated that the structural properties of the conjugated RNAs showed similar...