Isopentenyl Diphosphate Isomerase (IPI) Gene Silencing Negatively Affects Patchouli Alcohol Biosynthesis in Pogostemon cablin

Pogostemon cablin is a medicinally and economically important plant because it contains a high content of patchouli oil. Patchouli oil is composed of more than 24 unique sesquiterpene compounds, with the most abundant being patchouli alcohol (PA). PA is a sesquiterpene and is mainly synthesized through the mevalonate (MVA) pathway in plants in which isopentenyl diphosphate isomerase (IPI) is a key enzyme. Here, a full-length cDNA encoding IPI...