Simultaneously performed combined 24-2 and 10-2 visual field tests in glaucoma.

Published on Jan 13, 2021in Scientific Reports3.998
· DOI :10.1038/S41598-020-80318-W
Kyoung In Jung12
Estimated H-index: 12
(Catholic University of Korea),
Hee Kyung Ryu1
Estimated H-index: 1
(Catholic University of Korea)
+ 2 AuthorsChan Kee Park27
Estimated H-index: 27
(Catholic University of Korea)
Using either 24-2 or 10-2 visual field (VF) testing only is not enough to cover all the various types of glaucomatous VF defects. We investigated the performance of the combined 24-2 and 10-2 perimetry when conducted together and separately using the structure-function relationship. A total of 30 glaucoma patients with isolated peripheral nasal step, 37 patients with isolated paracentral scotoma, and 38 patients with both paracentral and nasal scotoma were included. To create the combined Humphrey VF test, a custom test pattern was established using the built-in custom point options, an example of the X, Y coordinate system. In glaucoma patients with peripheral nasal step, the superotemporal topographic structure-function relationship with peripapillary retinal nerve fiber layer (RNFL) thickness was superior in relation to the combined or 24-2 perimetry relative to the 10-2 perimetry (both P < 0.05). The combined VF test showed more favorable inferotemporal or inferonasal structure-function correlation with the corresponding ganglion cell-inner plexiform layer (GCIPL) thickness when compared with results gleaned using the 24-2 VF test (P < 0.05). Simultaneously performed 24-2 and 10-2 VF tests demonstrated a superior topographic structure-function relationship when compared with them separately performed in some sectors.
#1Jack Phu (UNSW: University of New South Wales)H-Index: 11
#2Michael Kalloniatis (UNSW: University of New South Wales)H-Index: 35
Abstract Purpose To compare the ability of 24-2 and 24-2C test grids in measuring visual field global indices, identifying central visual field defects and facilitating macular structure-function analysis with optical coherence tomography (OCT) scans in glaucoma suspects and glaucoma patients. Design Prospective, cross-sectional study Participants One eye from 100 glaucoma suspect and glaucoma patients (60 undergoing SITA-Faster testing on 24-2 and 24-2C; 40 undergoing SITA-Standard testing on 2...
12 CitationsSource
#1C Gustavo De Moraes (CUMC: Columbia University Medical Center)H-Index: 10
#2Donald C. Hood (Columbia University)H-Index: 84
Last. Jeffrey M. Liebmann (CUMC: Columbia University Medical Center)H-Index: 95
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Purpose To investigate the prevalence of visual field defects in glaucomatous eyes, glaucoma suspects, and ocular hypertensives with 24-2 and 10-2 visual fields. Design Prospective, cross-sectional study. Participants Patients with or suspected glaucoma tested with 24-2 and 10-2. Patients were classified into 3 groups on the basis of the presence of glaucomatous optic neuropathy (GON) and 24-2 visual field abnormalities: early glaucoma (GON and abnormal visual field, mean deviation >−6 decibels ...
88 CitationsSource
Purpose To simulate modified versions of the 24-2 (6° grid) visual field (VF) test pattern by adding points from the 10-2 (2° grid) test pattern, and to assess their ability to detect early glaucomatous defects in the central 10°.
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Importance The macula is essential for visual functioning and is known to be affected even in early glaucoma. However, little is currently understood about the prevalence and nature of central vision loss in early glaucoma. Objective To determine the prevalence and characteristics of visual field (VF) defects in the central 10° in glaucoma suspects and patients with mild glaucoma using a prospective design. Design, Setting, and Participants This prospective observational cohort study was conduct...
126 CitationsSource
#1Sung Chul Park (NYMC: New York Medical College)H-Index: 16
#2Yungtai Kung (NYMC: New York Medical College)H-Index: 3
Last. Robert Ritch (NYMC: New York Medical College)H-Index: 99
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Objective To compare the performance of 10-2 versus 24-2 visual fields (VFs) in detecting progression of initial parafoveal scotoma (IPFS) in glaucomatous eyes. Design Retrospective, observational study. Participants Glaucoma patients with the following criteria: (1) an IPFS (≥3 adjacent points with P P Methods Based on threshold map sensitivities, VF progression, defined as having 1 or more significantly progressing point(s) with a slope of sensitivity of less than –1.0 dB/year at P Main Outcom...
61 CitationsSource
#1Mauro T. Leite (UCSD: University of California, San Diego)H-Index: 16
#2Linda M. ZangwillH-Index: 96
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Purpose: To evaluate the relationship between glaucomatous structural damage assessed by the Cirrus Spectral Domain OCT (SDOCT) and functional loss as measured by standard automated perimetry (SAP). Methods: Four hundred twenty-two eyes (78 healthy, 210 suspects, 134 glaucomatous) of 250 patients were recruited from the longitudinal Diagnostic Innovations in Glaucoma Study and from the African Descent and Glaucoma Evaluation Study. All eyes underwent testing with the Cirrus SDOCT and SAP within ...
84 CitationsSource
#1Michael Wall (UI: University of Iowa)H-Index: 56
#2K. R. WoodwardH-Index: 8
Last. Paul H. Artes (Dal: Dalhousie University)H-Index: 29
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98 CitationsSource
#1Donald L. Budenz (UM: University of Miami)H-Index: 59
#2Paul Rhee (UM: University of Miami)H-Index: 5
Last. Douglas R. Anderson (UM: University of Miami)H-Index: 57
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Objectives To compare the severity, size, and depth of glaucomatous visual field defects using standard full threshold (FT), Swedish interactive threshold algorithm (SITA) standard (SS), and SITA fast (SF) algorithms of the Humphrey perimeter. Methods A prospective observational case series of 77 patients with glaucoma performed FT, SS, and SF 30-2 white-on-white testing programs on the same day on 2 occasions for 1 month. The severity of defects was compared using the mean deviation, pattern st...
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#2Graham E. Holder (Moorfields Eye Hospital)H-Index: 64
Last. Roger A. HitchingsH-Index: 69
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PURPOSE. To evaluate the relationship between electrophysiological, psychophysical, and structural measurements in normal and glaucomatous eyes and to test the hypothesis that there is a continuous structure–function relationship between ganglion cell numbers and visual field sensitivity. METHODS. Thirty-four normal subjects and 40 patients with glaucoma were examined with the pattern electroretinogram (PERG), perimetry and retinal tomography. Transient and steady state (SS) PERGs were recorded,...
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Cited By1
#1Jack Phu (UNSW: University of New South Wales)H-Index: 11
#2Michael Kalloniatis (UNSW: University of New South Wales)H-Index: 35
Abstract Objectives To compare the ability of 24-2C and 10-2 test grids in measuring visual field global indices, identifying central visual field defects, and facilitating macular structure-function analysis with optical coherence tomography (OCT) scans in glaucoma suspects and glaucoma patients. Design Prospective, cross-sectional study. Participants One eye from 131 glaucoma and 57 glaucoma suspect patients recruited from a referral-only university-based glaucoma clinic. Methods Each subject ...