Abstract
Primary immunodeficiencies (PID) are a heterogeneous group of diseases, mostly inherited, caused by more than 400 intrinsic disorders of the immune system. Patients suffer from frequent and recurrent infections as well as the symptoms of immune dysregulation such as autoimmunity, lymphoproliferation, granulomas, chronic lung diseases, and susceptibility to malignancies. Seven different immune deficiency states, which are transmitted with the X...
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