Feasibility of Real-Time Myocardial Contrast Echocardiography to Detect Cardiac Allograft Vasculopathy in Pediatric Heart Transplant Recipients

•CAV causes significant morbidity in pediatric heart transplant recipients. •CAV is difficult to detect by conventional noninvasive techniques. •RTMCE during DSE was feasible and safe in 36 pediatric heart transplant recipients. •Perfusion analysis identified CAV when compared with invasive coronary angiography. •RTMCE may be a valuable approach to CAV screening in pediatric transplant patients. Background Cardiac allograft vasculopathy (CAV) is...