Implant functionalization with mesoporous silica: A promising antibacterial strategy, but does such an implant osseointegrate?

New strategies for implant surface functionalization in the prevention of peri-implantitis while not compromising osseointegration are currently explored. The aim of this in vivo study was to assess the osseointegration of a titanium-silica composite implant, previously shown to enable controlled release of therapeutic concentrations of chlorhexidine, in the Göttingen mini-pig oral model.Three implant groups were designed: macroporous titanium...