A randomized control trial of duloxetine and gabapentin in painful diabetic neuropathy

To analyze the efficacy and safety of duloxetine and gabapentin in painful diabetic neuropathy (PDN).A randomized, open-label, active control, 12-week trial was conducted. A total of 86 participants were randomized in 1:1 ratio into gabapentin 300 mg and duloxetine 60 mg groups. The primary efficacy objective was comparison of mean change in Visual Analogue Scale (VAS) (0-100 points) scores between duloxetine and gabapentin. The symptom scores...