Upregulation of peroxisome proliferator-activated receptor-α and the lipid metabolism pathway promotes carcinogenesis of ampullary cancer

Ampullary cancer is a rare periampullary cancer currently with no targeted therapeutic agent.It is important to develop a deeper understanding of the carcinogenesis of ampullary cancer.We attempted to explore the characteristics of ampullary cancer in our dataset and a public database, followed by a search for potential drugs.We used a bioinformatics pipeline to analyze complementary (c)DNA microarray data of ampullary cancer and surrounding...