PET imaging of net availability in humans using [ 11 C]MRB: Age, gender and ethnicity effects
Volume: 16, Issue: S4
Published: Dec 1, 2020
Abstract
Background Understanding the underlying pathological mechanisms of AD is urgently needed to enable the development of effective treatments. Tau pathology emerges decades before amyloid pathology, appearing first in the brainstem (BS); particularly in the locus coeruleus (LC), the source of brain’s norepinephrine (NE). Our preliminary data using [ 11 C]MRB have documented an age‐related decline in NE transporters (NET) starting in middle age,...
Paper Details
Title
PET imaging of net availability in humans using [ 11 C]MRB: Age, gender and ethnicity effects
Published Date
Dec 1, 2020
Volume
16
Issue
S4
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