Original paper
Two high-rate pentose-phosphate pathways in cancer cells
Abstract
The relevant role of pentose phosphate pathway (PPP) in cancer metabolic reprogramming has been usually outlined by studying glucose-6-phosphate dehydrogenase (G6PD). However, recent evidence suggests an unexpected role for a less characterized PPP, triggered by hexose-6-phosphate dehydrogenase (H6PD) within the endoplasmic reticulum (ER). Studying H6PD biological role in breast and lung cancer, here we show that gene silencing of this reticular...
Paper Details
Title
Two high-rate pentose-phosphate pathways in cancer cells
Published Date
Dec 17, 2020
Journal
Volume
10
Issue
1
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Notes
History