Ectopic Lymphoid Follicles in Multiple Sclerosis: Centers for Disease Control?
Abstract
While the contribution of autoreactive CD4 + T cells to the pathogenesis of Multiple Sclerosis (MS) is widely accepted, the advent of B cell-depleting monoclonal antibody (mAb) therapies has shed new light on the complex cellular mechanisms underlying MS pathogenesis. Evidence supports the involvement of B cells in both antibody-dependent and -independent capacities. T cell-dependent B cell responses originate and take shape in germinal centers...
Paper Details
Title
Ectopic Lymphoid Follicles in Multiple Sclerosis: Centers for Disease Control?
Published Date
Dec 8, 2020
Journal
Volume
11
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