Effectiveness of early treatment of lopinavir–ritonavir in patients with severe COVID-19: a case series

ABSTRACT

Aim

The inconsistent effects of lopinavir–ritonavir (LPV/r) on COVID-19 seem to be caused by the therapeutic window. In the present study, we aim to present the effects of early LPV/r treatment on patients with severe COVID-19.

Methods

The demographics, characteristics, treatments, SARS-CoV-2 test results and outcomes of 19 patients with severe COVID-19 treated with LPV/r within 12 days of onset of symptoms...