Tumor Burden Dictates Prognosis Among Patients Undergoing Resection of Intrahepatic Cholangiocarcinoma: A Tool to Guide Post-Resection Adjuvant Chemotherapy?

Diamantis I. Tsilimigras; J. Madison Hyer; Anghela Z. Paredes; Dimitrios Moris; Kota Sahara; Alfredo Guglielmi; Luca Aldrighetti; Matthew J. Weiss; Todd W. Bauer; Sorin Alexandrescu; Xu-Feng Zhang; Timothy M. Pawlik

doi:https://doi.org/10.1245/s10434-020-09393-7

doi.org/10.1245/s10434-020-09393-7

Tumor Burden Dictates Prognosis Among Patients Undergoing Resection of Intrahepatic Cholangiocarcinoma: A Tool to Guide Post-Resection Adjuvant Chemotherapy?

Diamantis I. Tsilimigras

34

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J. Madison Hyer

25

,

..., Timothy M. Pawlik

107

Annals of Surgical Oncology3.70

Volume: 28, Issue: 4, Pages: 1970 - 1978

Published: Dec 1, 2020

Abstract

While tumor burden (TB) has been associated with outcomes among patients with hepatocellular carcinoma, the role of overall TB in intrahepatic cholangiocarcinoma (ICC) remains poorly defined. Patients undergoing curative-intent resection of ICC between 2000 and 2017 were identified from a multi-institutional database. The impact of TB on overall (OS) and disease-free survival (DFS) was evaluated in the multi-institutional database and validated...