Disease modeling and stem cell immunoengineering in regenerative medicine using CRISPR/Cas9 systems

Volume: 18, Pages: 3649 - 3665
Published: Jan 1, 2020
Abstract
CRISPR/Cas systems are popular genome editing tools that belong to a class of programmable nucleases and have enabled tremendous progress in the field of regenerative medicine. We here outline the structural and molecular frameworks of the well-characterized type II CRISPR system and several computational tools intended to facilitate experimental designs. The use of CRISPR tools to generate disease models has advanced research into the molecular...
Paper Details
Title
Disease modeling and stem cell immunoengineering in regenerative medicine using CRISPR/Cas9 systems
Published Date
Jan 1, 2020
Volume
18
Pages
3649 - 3665
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