Biomolecule-Directed Carbon Nanotube Self-Assembly.

Published on Jan 1, 2021in Advanced Healthcare Materials7.367
· DOI :10.1002/ADHM.202001162
Eduardo Anaya-Plaza8
Estimated H-index: 8
(Aalto University),
Ahmed Shaukat3
Estimated H-index: 3
(Aalto University)
+ 1 AuthorsMauri A. Kostiainen36
Estimated H-index: 36
(Aalto University)
Sources
Abstract
The strategy of combining biomolecules and synthetic components to develop biohybrids is becoming increasingly popular for preparing highly customized and biocompatible functional materials. Carbon nanotubes (CNTs) benefit from bioconjugation, allowing their excellent properties to be applied to biomedical applications. This study reviews the state-of-the-art research in biomolecule-CNT conjugates and discusses strategies for their self-assembly into hierarchical structures. The review focuses on various highly ordered structures and the interesting properties resulting from the structural order. Hence, CNTs conjugated with the most relevant biomolecules, such as nucleic acids, peptides, proteins, saccharides, and lipids are discussed. The resulting well-defined composites allow the nanoscale properties of the CNTs to be exploited at the micro- and macroscale, with potential applications in tissue engineering, sensors, and wearable electronics. This review presents the underlying chemistry behind the CNT-based biohybrid materials and discusses the future directions of the field.
📖 Papers frequently viewed together
20166.89Nanoscale
6 Authors (Dapeng Li, ..., Gang Wei)
133 Citations
5 Authors (Wenrong Yang, ..., Filip Braet)
512 Citations
References154
Newest
#6Ying Wang (HEU: Harbin Engineering University)H-Index: 6
Abstract The on-line electrochemical analysis is one of powerful strategies in analytical chemistry and pathophysiology. To achieve high sensitivity and long-term stability of electrochemical biosensor, the bottleneck challenge is the spontaneous proteins adsorption onto the electrode surface within the biological fluids or in vivo environments. In this work, a hemoglobin/gelatin-multiwalled carbon nanotubes microbelts modified electrode (Hb/gelatin-MWCNTs/GC electrode) was successfully fabricat...
2 CitationsSource
#1Ahmed Shaukat (Aalto University)H-Index: 3
#2Eduardo Anaya-Plaza (Aalto University)H-Index: 8
Last. Mauri A. Kostiainen (Aalto University)H-Index: 36
view all 7 authors...
In this communication, electrostatically assembled phthalocyanine (Pc)-DNA origami (DO) complexes are formed and their optical properties are demonstrated. The formation of the complex prevents the Pc aggregation, thus yielding an enhanced optical response and photooxidative resilience towards aggregation in biologically-related media. Simultaneously, the Pc protects the DO against enzymatic digestion. Both features solve previous drawbacks associated with phthalocyanine photosensitizers and DNA...
5 CitationsSource
#1Li Chen (Sichuan University)H-Index: 62
#2Kun Guo (MUC: Minzu University of China)H-Index: 2
Last. Bang-Jing Li (CAS: Chinese Academy of Sciences)H-Index: 26
view all 7 authors...
Abstract Efficient, flexible and self-healing electromagnetic interference (EMI) shielding materials are highly desirable and valuable for electromagnetic shielding industry. Furthermore, in order to achieve a commercial-grade EMI shielding effectiveness, a large amount of filler is required. Here, a kind of self-healing EMI shielding fabric was fabricated by preparing aligned carbon nanotube-poly (2-hydroxyethyl methacrylate) (CNT-PHEMA) non-woven fabric through magnetic-field-assisted electros...
16 CitationsSource
#1Xing Zhou (MediaTech Institute)H-Index: 17
#2Jian SuH-Index: 8
Last. Zhigang Huang (BTBU: Beijing Technology and Business University)H-Index: 5
view all 8 authors...
Abstract With the development of nanobiotechnology, the carbon nanotubes (CNTs) and protein hybrids system has attracted an increasing attention for great potential application in nanotechnology, medicine, smart materials, light industry, and biology. In this review, the main preparation processes, impact factors, measurement of interactions and potential applications of CNTs/protein are presented from the aspect of experiments. Meanwhile, the proper forces detection methods are illustrated comp...
25 CitationsSource
#1James K. Utterback (University of California, Berkeley)H-Index: 7
#2Jesse L. Ruzicka (CU: University of Colorado Boulder)H-Index: 3
Last. Gordana Dukovic (CU: University of Colorado Boulder)H-Index: 22
view all 5 authors...
This review summarizes progress in understanding electron transfer from photoexcited nanocrystals to redox enzymes. The combination of the light-harvesting properties of nanocrystals and the cataly...
12 CitationsSource
#8Kai Liu (THU: Tsinghua University)H-Index: 63
Aligning carbon nanotubes (CNTs) is a key challenge for fabricating CNT-based electronic devices. Herein, we report a spherical nucleic acid (SNA) mediated approach for the highly precise alignment of CNTs at prescribed sites on DNA origami. We find that the cooperative DNA hybridization occurring at the interface of SNA and DNA-coated CNTs leads to an approximately five-fold improvement of the positioning efficiency. By combining this with the intrinsic positioning addressability of DNA origami...
9 CitationsSource
#1Stefano Cestellos-Blanco (University of California, Berkeley)H-Index: 8
#2Hao Zhang (University of California, Berkeley)H-Index: 15
Last. Peidong YangH-Index: 187
view all 5 authors...
Photosynthetic semiconductor biohybrids integrate the best attributes of biological whole-cell catalysts and semiconducting nanomaterials. Enzymatic machinery enveloped in its native cellular environment offers exquisite product selectivity and low substrate activation barriers while semiconducting nanomaterials harvest light energy stably and efficiently. In this Review Article, we illustrate the evolution and advances of photosynthetic semiconductor biohybrids focusing on the conversion of CO2...
57 CitationsSource
#1Adrian Keller (University of Paderborn)H-Index: 25
#2Veikko LinkoH-Index: 25
DNA nanotechnology holds substantial promise for future biomedical engineering and the development of novel therapies and diagnostic assays. The subnanometer-level addressability of DNA nanostructures allows for their precise and tailored modification with numerous chemical and biological entities, which makes them fit to serve as accurate diagnostic tools and multifunctional carriers for targeted drug delivery. The absolute control over shape, size, and function enables the fabrication of tailo...
50 CitationsSource
#1Guoxu Zhao (Xi'an Jiaotong University)H-Index: 7
#2Xu Zhang (Xi'an Jiaotong University)H-Index: 1
Last. Xiaohui Zhang (Xi'an Jiaotong University)H-Index: 31
view all 6 authors...
Cardiac tissue engineering holds great potential in regenerating functional cardiac tissues for various applications. The major strategy is to design scaffolds recapitulating the native cardiac microenvironment to enhance cell and tissue functionalities. Among various biomaterial systems, nanofibrous matrices with aligned morphologies and enhanced conductivity incline to induce the formation of oriented engineered cardiac tissues with enhanced functionalities. The challenge is to functionalize t...
16 CitationsSource
#1Li Liu (SCNU: South China Normal University)H-Index: 2
#2Bo Yang (SCNU: South China Normal University)H-Index: 1
Last. Yan-Qing Guan (SCNU: South China Normal University)H-Index: 9
view all 10 authors...
The use of bone tissue engineering scaffolds has become a promising potential treatment for bone defects as they expedite bone healing. A carbon nanotube–hydroxyapatite (CNT–HA) composite can accelerate the growth of cells. However, the molecular organized arrangement of organic and inorganic components is one of the most important biochemical phenomena in the formation of bones. This study aimed to prepare ordered CNT–HA scaffolds by applying agarose gel electrophoresis to imitate a biomimetic ...
11 CitationsSource
Cited By5
Newest
#1Myriam Barrejón (UniTS: University of Trieste)H-Index: 11
#2Silvia Marchesan (UniTS: University of Trieste)H-Index: 29
Last. Maurizio Prato (Ikerbasque)H-Index: 123
view all 4 authors...
Abstract null null Carbon nanotubes (CNTs) have appeared in recent years as innovative components for the development of the next-generation scaffolds to regenerate damaged cardiac tissue. The unique robustness, mechanical and electronic properties of CNTs, along with their ease to undergo chemical modification, make them promising candidates for the design of engineered cardiac constructs with ad hoc properties. The integration of CNTs with polymeric scaffolds is a promising strategy for cardia...
Source
#1Amalia Mezei (CSIC: Spanish National Research Council)H-Index: 3
#2Ramon Pons (CSIC: Spanish National Research Council)H-Index: 29
Cationic surfactants interact with DNA (Deoxyribonucleic acid), forming surfactant-DNA complexes that offer particularly efficient control for encapsulation and release of DNA from DNA gel particles. In the present work, DNA-based particles were prepared using CTAB (Cetyltrimethylammonium bromide) as the cationic surfactant and modified using two different additives: (Multi-Walled Carbon Nanotubes) MWNT or PEG (Poly Ethylene Glycol). The use of both additives to form composites increased the sta...
Source
#1Eleana Manousiouthakis (UF: University of Florida)
#2Junggeon Park (Gwangju Institute of Science and Technology)H-Index: 8
Last. Christine E. Schmidt (UF: University of Florida)H-Index: 60
view all 5 authors...
Abstract null null Carbon-based conductive and electroactive materials (e.g., derivatives of graphene, fullerenes, polypyrrole, polythiophene, polyaniline) have been studied since the 1970s for use in a broad range of applications. These materials have electrical properties comparable to those of commonly used metals, while providing other benefits such as flexibility in processing and modification with biologics (e.g., cells, biomolecules), to yield electroactive materials with biomimetic mecha...
Source
#1Simone AdorinniH-Index: 1
Last. Silvia MarchesanH-Index: 29
view all 5 authors...
5 CitationsSource