Biodegradable metal-derived magnesium and sodium enhances bone regeneration by angiogenesis aided osteogenesis and regulated biological apatite formation

Biodegradable metals have great attraction to become orthopaedic implants. Here, we demonstrated a biodegradable magnesium alloy incorporated with essential element sodium through Sn-Na master alloying technique. The designed MgSnZnNa alloy presented better hardness and corrosion resistance due to the uniform distribution of Na in Mg2Sn second phase and solid soluble Zn in Mg matrix. The co-release of Mg and Na ions resulted in advanced...