Epigenome-wide association study identifies DNA methylation sites associated with target organ damage in older African Americans
Abstract
Target organ damage (TOD) manifests as vascular injuries in the body organ systems associated with long-standing hypertension. DNA methylation in peripheral blood leukocytes can capture inflammatory processes and gene expression changes underlying TOD. We investigated the association between epigenome-wide DNA methylation and five measures of TOD (estimated glomerular filtration rate (eGFR), urinary albumin-creatinine ratio (UACR), left...
Paper Details
Title
Epigenome-wide association study identifies DNA methylation sites associated with target organ damage in older African Americans
Published Date
Oct 26, 2020
Journal
Volume
16
Issue
8
Pages
862 - 875
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