Functional Heterogeneity of Perivascular Precursor Cells

Tissue-resident mesenchymal precursor cells occupy perivascular spaces. Two main perivascular locations have been described for forerunners of cultured mesenchymal stem cells, including a subendothelial location (termed pericytes) and cells within the tunica adventitia (termed adventitial cells). Emerging data have made clear the cellular heterogeneity within the perivascular stem cell niche. This brief review focuses on two issues. First, the...