Concepts of extracellular matrix remodelling in tumour progression and metastasis
Abstract
Tissues are dynamically shaped by bidirectional communication between resident cells and the extracellular matrix (ECM) through cell-matrix interactions and ECM remodelling. Tumours leverage ECM remodelling to create a microenvironment that promotes tumourigenesis and metastasis. In this review, we focus on how tumour and tumour-associated stromal cells deposit, biochemically and biophysically modify, and degrade tumour-associated ECM. These...
Paper Details
Title
Concepts of extracellular matrix remodelling in tumour progression and metastasis
Published Date
Oct 9, 2020
Journal
Volume
11
Issue
1
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