Original paper
Untargeted longitudinal analysis of a wellness cohort identifies markers of metastatic cancer years prior to diagnosis
Abstract
We analyzed 1196 proteins in longitudinal plasma samples from participants in a commercial wellness program, including samples collected pre-diagnosis from ten cancer patients and 69 controls. For three individuals ultimately diagnosed with metastatic breast, lung, or pancreatic cancer, CEACAM5 was a persistent longitudinal outlier as early as 26.5 months pre-diagnosis. CALCA, a biomarker for medullary thyroid cancer, was hypersecreted in...
Paper Details
Title
Untargeted longitudinal analysis of a wellness cohort identifies markers of metastatic cancer years prior to diagnosis
Published Date
Oct 1, 2020
Journal
Volume
10
Issue
1
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Notes
History