Review paper
Small molecules regulating reactive oxygen species homeostasis for cancer therapy
Abstract
Elevated intracellular reactive oxygen species (ROS) and antioxidant defense systems have been recognized as one of the hallmarks of cancer cells. Compared with normal cells, cancer cells exhibit increased ROS to maintain their malignant phenotypes and are more dependent on the "redox adaptation" mechanism. Thus, there are two apparently contradictory but virtually complementary therapeutic strategies for the regulation of ROS to prevent or...
Paper Details
Title
Small molecules regulating reactive oxygen species homeostasis for cancer therapy
Published Date
Sep 27, 2020
Journal
Volume
41
Issue
1
Pages
342 - 394