Halogenation as a tool to tune antimicrobial activity of peptoids
Abstract
Antimicrobial peptides have attracted considerable interest as potential new class of antibiotics against multi-drug resistant bacteria. However, their therapeutic potential is limited, in part due to susceptibility towards enzymatic degradation and low bioavailability. Peptoids (oligomers of N -substituted glycines) demonstrate proteolytic stability and better bioavailability than corresponding peptides while in many cases retaining...
Paper Details
Title
Halogenation as a tool to tune antimicrobial activity of peptoids
Published Date
Sep 9, 2020
Journal
Volume
10
Issue
1
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