Biomimetic Approach for Highly Selective Artificial Water Channels Based on Tubular Pillar[5]arene Dimers

Artificial water channels mimicking natural aquaporins (AQPs) can be used for selective and fast transport of water. Here, we quantify the transport performances of peralkyl‐carboxylate‐pillar[5]arenes dimers in bilayer membranes. They can transport ≈10 7 water molecules/channel/second, within one order of magnitude of the transport rates of AQPs, rejecting Na + and K + cations. The dimers have a tubular structure, superposing pillar[5]arene...