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Original paper

Molecular Mechanisms of CRISPR-Cas Immunity in Bacteria

Volume: 54, Issue: 1, Pages: 93 - 120
Published: Aug 28, 2020
Abstract
Prokaryotes have developed numerous defense strategies to combat the constant threat posed by the diverse genetic parasites that endanger them. Clustered regularly interspaced short palindromic repeat (CRISPR)-Cas loci guard their hosts with an adaptive immune system against foreign nucleic acids. Protection starts with an immunization phase, in which short pieces of the invader's genome, known as spacers, are captured and integrated into the...
Paper Details
Title
Molecular Mechanisms of CRISPR-Cas Immunity in Bacteria
Published Date
Aug 28, 2020
Volume
54
Issue
1
Pages
93 - 120
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