Original paper
Interaction of glycated and acetylated human α2-antiplasmin with fibrin clots
Abstract
: In type 2 diabetes mellitus (T2DM), increased α2-antiplasmin incorporation in fibrin and impaired fibrinolysis have been reported. Acetylsalicylic acid (ASA), used in cardiovascular prevention, modulates fibrinolysis and exerts weaker therapeutic effect in this disease. We investigated how glycation and acetylation of α2-antiplasmin affects its interaction with fibrin. Using surface plasmon resonance, we analyzed fibrin binding by...
Paper Details
Title
Interaction of glycated and acetylated human α2-antiplasmin with fibrin clots
Published Date
Jul 18, 2020
Volume
31
Issue
6
Pages
393 - 396
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Notes
History