The food contaminant deoxynivalenol provokes metabolic impairments resulting in non-alcoholic fatty liver (NAFL) in mice

Rym Barbouche; Stéphanie Gaigé; Coraline Airault; Kevin Poirot; Michel Dallaporta; Jean-Denis Troadec; Anne Abysique

doi:https://doi.org/10.1038/s41598-020-68712-w

doi.org/10.1038/s41598-020-68712-w

The food contaminant deoxynivalenol provokes metabolic impairments resulting in non-alcoholic fatty liver (NAFL) in mice

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..., Anne Abysique

10

Scientific Reports4.60

Volume: 10, Issue: 1

Published: Jul 21, 2020

Abstract

The ribotoxin deoxynivalenol (DON) is a trichothecene found on cereals responsible for mycotoxicosis in both humans and farm animals. DON toxicity is characterized by reduced food intake, diminished nutritional efficiency and immunologic effects. The present study was designed to further characterize the alterations in energy metabolism induced by DON intoxication. We demonstrated that acute DON intoxication triggered liver steatosis associated...

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Paper Details

Title

The food contaminant deoxynivalenol provokes metabolic impairments resulting in non-alcoholic fatty liver (NAFL) in mice

DOI

doi.org/10.1038/s41598-020-68712-w

Published Date

Jul 21, 2020

Journal

Scientific Reports

Volume

10

Issue

1

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