Original paper
Leptin Promotes Prostate Cancer Proliferation and Migration by Stimulating STAT3 Pathway
Abstract
To better understand the link between obesity and prostate cancer (PC) aggressiveness, we investigate the role of leptin, an obesity associated adipokine, and its receptor (Ob-R) in PC cells migration. The migration assay (Wound-healing) was used to study the leptin impact on DU-145 and PC3 cells lines. STAT3 activation was performed by Western Blot. E-cadherin expression was studied using fluorescence microscopy and Ob-R expression in PC and...
Paper Details
Title
Leptin Promotes Prostate Cancer Proliferation and Migration by Stimulating STAT3 Pathway
Published Date
Jul 22, 2020
Journal
Volume
73
Issue
7
Pages
1217 - 1227
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Notes
History