We present a new bound on the ultra-light axion (ULA) dark matter mass $m_\text{a}$, using the Lyman-alpha forest to look for suppressed cosmic structure growth: a 95% lower limit $m_\text{a} > 2 \times 10^{-20}\,\text{eV}$. This strongly disfavors ($> 99.7\%$ credibility) the canonical ULA with $10^{-22}\,\text{eV} < m_\text{a} < 10^{-21}\,\text{eV}$, motivated by the string axiverse and solutions to possible tensions in the cold dark matter model. We strengthen previous equivalent bounds by about an order of magnitude. We demonstrate the robustness of our results using an optimized emulator of improved hydrodynamical simulations.