PROTAC: A promising technology for cancer treatment

Volume: 203, Pages: 112539 - 112539
Published: Oct 1, 2020
Abstract
Proteolysis-targeting chimeric molecules (PROTACs), which attract much more attention today, may be a potential way to treat cancer. PROTACs are made up of ligands of target proteins, E3 ligase recruiting elements and linkers. PROTACs can hijack the intracellular inherent ubiquitin proteasome system in cells to degrade different target proteins. PROTACs targeting different cancer-related proteins have been successfully developed and outperform...
Paper Details
Title
PROTAC: A promising technology for cancer treatment
Published Date
Oct 1, 2020
Volume
203
Pages
112539 - 112539
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