Pulmonary mechanics and gas exchange: a mathematical framework

In this paper, we model breathing at the level of a human alveolus by developing a novel mathematical framework that links pulmonary mechanics and gas exchange. Unlike previous models, the developed alveolar model comprises the alveolar gas mixture, capillaries perfused in the alveolar wall, pulmonary surfactant lining the alveolus and the pleural cavity. The inclusion of the multiple compartments affords interested researchers the chance to...